Lisa Howie will step down as executive director for the Bermuda National Gallery at the end of this month.
Ms Howie has worked at the gallery since 2006 and took over the top post three years later.
“I am extremely proud of what has been achieved and am deeply appreciative of the support I have enjoyed from a dedicated and professional staff,” she said.
“I also want to thank the many volunteers who enable the front desk reception each week and have played important roles in the many events and education programmes.
“It has been a privilege and honour to serve BNG as its executive director.
“I am grateful for the support of the chairman and the board of trustees for this opportunity.
Ms Howie added: “I will remain a champion of the BNG and wish the museum every success in the future. For the first time in over 25 years I am taking a pause on my career path to enjoy some precious moments to explore the next phase of my life.”
A spokeswoman for the gallery said that Ms Howie had worked hard in tough economic times to support the art and non-profit sectors.
Gary Phillips, BNG chairman, and Dawna Ferguson, deputy chair, thanked Ms Howie for her contributions to the development of the BNG.